Conjunctions between Saturn and Pluto have often coincided with viral epidemics and pandemics across history. Historical Saturn - Pluto conjunctions: 1318: Pisces - Great Famine: 1350: Aries - The Black Death: 1382: Taurus - Plague outbreak: 1413-14: Gemini - European plague outbreaks: 1445-46: Cancer - European plague outbreaks: 1480: Libra - Italian Plague: 1518: Capricorn - Smallpox Epidemic in the Aztec Empire: 1552: Pisces & Aquarius - Cocoliztli Epidemic: 1585: Aries -